Rivaroxaban Impurity 19, CAS 482308-13-4, es una impureza heteroaromática de bajo peso molecular asociada con la química sintética de rivaroxabán y definida por la fórmula C10H13N3O2 y un peso molecular de 207,22 g/mol. Su motivo estructural es compatible con un intermedio relacionado con el proceso o un subproducto generado por conversión incompleta de grupos funcionales durante el ensamblaje del andamiaje anticoagulante unido a oxazolidinona. Dado que estas impurezas pueden persistir a nivel traza y modificar el perfil de impurezas, la caracterización suele requerir LC-MS/MS, LC-MS de alta resolución y HPLC complementaria con detección UV o de arreglo de diodos. Su interpretación se integra en marcos regulatorios que evalúan origen, destino y relevancia toxicológica.
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