Aceclofenac EP Impurity E
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139272-67-6Aceclofenac EP Impurity E

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Catalogue No.:VL284003
CAS No.:139272-67-6
Mol. Formula:C18H17Cl2NO4
Mol. Weight:382.24 g/mol

Additional information on CAS 139272-67-6

Parent drug

Aceclofenac

IUPAC Name

Ethyl [[[2-[(2, 6-dichlorophenyl) amino] phenyl] acetyl] oxy] acetate

Pharmacopoeial Synonyms

Aceclofenac Ethyl Ester

Other Synonyms

Aceclofenac Impurity E; Ethyl aceclofenac; Ethyl Ester of Aceclofenac; 2-Ethoxy-2-oxoethyl 2-(2-(2,6-dichlorophenylamino)-phenyl)acetate; (2-ethoxy-2-oxoethyl) 2-[2-(2,6-dichloroanilino)phenyl]acetate; Benzeneacetic acid, 2-((2,6-dichlorophenyl)amino)-, 2-ethoxy-2-oxoethyl ester

Description

Aceclofenac EP Impurity E (CAS No: 139272-67-6) or Ethyl [[[2-[(2,6-dichlorophenyl) amino] phenyl] acetyl] oxy] acetate is an impurity formed during the industrial synthesis of Aceclofenac that is an orally administered phenylacetic acid derivative having effects on numerous inflammatory mediators.

References

Karbhari, PradnyaA, et al. “RP-LC Gradient Elution Method for Simultaneous Determination of Thiocolchicoside, Aceclofenac and Related Impurities in Tablet Formulation.” Journal of Pharmacy and Bioallied Sciences, vol. 6, no. 4, 2014, p. 246, https://doi.org/10.4103/0975-7406.142955. Dooley, Mukta, et al. “Aceclofenac.” Drugs, vol. 61, no. 9, 2001, pp. 1351–78, https://doi.org/10.2165/00003495-200161090-00012. ?

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