4'-Hydroxy Aceclofenac
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Documentation

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Includes: HPLC, MASS/LC-MS, 1H NMR, FT-IR, Potency, Structure Elucidation Report (SER), and additional analytical data depending on the product.

229308-90-14'-Hydroxy Aceclofenac

● Under Development

Catalogue No.:VL284012
CAS No.:229308-90-1
Mol. Formula:C16H13Cl2NO5
Mol. Weight:370.18 g/mol

Additional information on CAS 229308-90-1

Parent drug

Aceclofenac

IUPAC Name

2-[(2, 6-Dichloro-4-hydroxyphenyl)amino]benzeneacetic Acid Carboxymethyl Ester

Synonyms

N/A

Description

4'-Hydroxy Aceclofenac (CAS No: 229308-90-1) or 2-[(2,6-Dichloro-4-hydroxyphenyl)amino]benzeneacetic Acid Carboxymethyl Ester is a major metabolite of Aceclofenac that is a novel nonsteroidal anti-inflammatory drug (NSAID) used in patients with rheumatoid arthritis and osteoarthritis.

References

?Yamazaki, R., et al. “A Major Metabolite of Aceclofenac, 4?-Hydroxy Aceclofenac, Suppresses the Production of Interstitial Pro-Collagenase/ProMMP-1 and Pro-Stromelysin-1/ProMMP-3 by Human Rheumatoid Synovial Cells.” Inflammation Research, vol. 49, no. 3, Mar. 2000, pp. 133–38, https://doi.org/10.1007/s000110050571. ?

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