Diclofenac Chloroacetyl Impurity (CAS No.: 15308-01-7) is an impurity of Diclofenac which is a potent nonsteroidal anti-inflammatory drug (NSAID) of the phenylacetic acid class. Diclofenac attaches efficaciously to plasma albumin and its oral absorption is rapid and complete. It shows good antipyretic and analgesic properties.
References
Orlandini, S., et al. “A Comprehensive Strategy in the Development of a Cyclodextrin-Modified Microemulsion Electrokinetic Chromatographic Method for the Assay of Diclofenac and Its Impurities: Mixture-Process Variable Experiments and Quality by Design.†Journal of Chromatography A, vol. 1466, Sept. 2016, pp. 189–98, https://doi.org/10.1016/j.chroma.2016.09.013.?Davies, Neal M., and Keith E. Anderson. “Clinical Pharmacokinetics of Diclofenac.†Clinical Pharmacokinetics, vol. 33, no. 3, Sept. 1997
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