Diclofenac EP Impurity E
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59-48-3Diclofenac EP Impurity E

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Catalogue No.:VL48018
CAS No.:59-48-3
Mol. Formula:C8H7NO
Mol. Weight:133.15 g/mol

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100 mg $129.00
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Additional information on CAS 59-48-3

Parent drug

Diclofenac

Characterization Data (Included)

HPLC, MASS/LC-MS, 1H NMR, FT-IR, Potency, and Structure Elucidation Report (SER).

Additional Characterization Data

QNMR, D2O Exchange, 13C NMR, 13C APT, COSY NMR, NOESY NMR, 15N NMR, HSQC NMR, HMQC NMR, and HMBC NMR. These are available upon request and may be free or subject to additional charges.

IUPAC Name

1,3-Dihydro-2H-indol-2-one

Pharmacopeial Synonyms

Oxindole; Diclofenac Related Compound E

Synonyms

2-Indolone; Indoline-2-one; 2-Oxo-2,3-dihydroindole; 2-Ketoindoline

Smiles

C1C2=CC=CC=C2NC1=O

InChI

InChI=1S/C8H7NO/c10-8-5-6-3-1-2-4-7(6)9-8/h1-4H,5H2,(H,9,10)

Shipping Condition

Ambient Temperature

Description

Diclofenac EP Impurity E, also referred to in pharmacopoeias as Oxindole; Diclofenac Related Compound E, is a meticulously characterized reference standard. It adheres to stringent regulatory guidelines, including those established by USP, EMA, JP, and BP. This product plays a vital role in Abbreviated New Drug Applications (ANDA), New Drug Applications (NDA), and the commercial manufacturing of Diclofenac. Furthermore, it is accompanied by a comprehensive Structure Elucidation Report (SER), ensuring its accuracy and reliability across various analytical applications. Also known as Diclofenac Related Compound E, Diclofenac Oxindole Impurity, Indolin-2-one, 1,3-Dihydro-2H-indol-2-one, 2-Indolinone, Oxindole, 2-Oxindole, 2-Oxoindoline or Diclofenac Oxindole Impurity is a metabolite of Diclofenac which is a non-steroidal anti-inflammatory agent (NSAID) to be accepted as a phenylacetic acid derivative and is known to compete with arachidonic acid for attaching to cyclo-oxygenase which results in the diminished formation of prostaglandins.

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