Aceclofenac EP Impurity C (CAS No: 15307-77-4) or Aceclofenac Impurity C / Diclofenac Ethyl Ester is formed during the production of Aceclofenac that is used In patients with osteoarthritis of the knee, basal and stimulated prostaglandin E2 production by blood mononuclear and polymorphonuclear cell inhibition.
References
Karbhari, PradnyaA, et al. “RP-LC Gradient Elution Method for Simultaneous Determination of Thiocolchicoside, Aceclofenac and Related Impurities in Tablet Formulation.” Journal of Pharmacy and Bioallied Sciences, vol. 6, no. 4, 2014, p. 246, https://doi.org/10.4103/0975-7406.142955. Brogden, Rex N., and Lynda R. Wiseman. “Aceclofenac.” Drugs, vol. 52, no. 1, July 1996, pp. 113–24, https://doi.org/10.2165/00003495-199652010-00008. ?
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