Aceclofenac EP Impurity D
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Includes: HPLC, MASS/LC-MS, 1H NMR, FT-IR, Potency, Structure Elucidation Report (SER), and additional analytical data depending on the product.

139272-66-5Aceclofenac EP Impurity D

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Catalogue No.:VL284002
CAS No.:139272-66-5
Mol. Formula:C17H15Cl2NO4
Mol. Weight:368.21 g/mol

Additional information on CAS 139272-66-5

Parent drug

Aceclofenac

IUPAC Name

Methyl [[[2-[(2, 6-dichlorophenyl)amino]phenyl] acetyl]oxy]acetate

Pharmacopoeial Synonyms

Aceclofenac Methyl Ester

Other Synonyms

Aceclofenac Impurity D; Methyl Aceclofenac; 2-Methoxy-2-oxoethyl 2-(2-(2,6-dichlorophenylamino)-phenyl)acetate; (2-methoxy-2-oxoethyl) 2-[2-(2,6-dichloroanilino)phenyl]acetate Benzeneacetic acid ; 2-[(2,6-dichlorophenyl)amino]-, 2-methoxy-2-oxoethyl ester

Description

Aceclofenac EP Impurity D (CAS No: 139272-66-5) or Methyl [[[2-[(2,6-dichlorophenyl)amino]phenyl] acetyl]oxy]acetate is a degradation product of Aceclofenac that is a phenylacetic acid derivative with anti-inflammatory and analgesic characteristics comparable to those of diclofenac.

References

Karbhari, PradnyaA, et al. “RP-LC Gradient Elution Method for Simultaneous Determination of Thiocolchicoside, Aceclofenac and Related Impurities in Tablet Formulation.” Journal of Pharmacy and Bioallied Sciences, vol. 6, no. 4, 2014, p. 246, https://doi.org/10.4103/0975-7406.142955. Brogden, Rex N., and Lynda R. Wiseman. “Aceclofenac.” Drugs, vol. 52, no. 1, July 1996, pp. 113–24, https://doi.org/10.2165/00003495-199652010-00008. ?

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