(4R-cis)-6-Chloromethyl-2,2-dimethyl-1,3-dioxane-4-acetic Acid tert-Butyl Ester (CAS No. 154026-94-5)Â is an impurity present in Rosuvastatin, Rosuvastatin is a synthetic, enantiomerically pure antilipemic agent, It is used to lower total cholesterol, low-density lipoprotein-cholesterol (LDL-C), apolipoprotein B, non-high-density lipoprotein-cholesterol and triglyceride plasma concentrations while increasing HDL-C concentrations, High LDL-C, low HDL-C and high TG concentrations in the plasma are associated with increased risk of atherosclerosis and cardiovascular disease.
References
Luvai, A., Mbagaya, W., Hall, A. S., & Barth, J. H. (2012). Rosuvastatin: A Review of the Pharmacology and Clinical Effectiveness in Cardiovascular Disease. Clinical Medicine Insights: Cardiology, 6, CMC.S4324. https://doi.org/10.4137/cmc.s4324
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