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80685-22-9Acyclovir Impurity 6
● In Stock
| Catalogue No.: | VE007787 |
|---|---|
| CAS No.: | 80685-22-9 |
| Mol. Formula: | C8H9N5O4 |
| Mol. Weight: | 239.19 g/mol |
Additional information on CAS 80685-22-9
Parent drug
AcyclovirIUPAC Name
2-((2-amino-6-oxo-1, 6-dihydro-9H-purin-9-yl)methoxy)acetic acidPharmacopoeial Synonyms
N/AOther Synonyms
2-[(2-amino-6-oxo-1H-purin-9-yl)methoxy]acetic acid; 2-((2-Amino-6-oxo-1H-purin-9(6H)-yl)methoxy)acetic acid; Acetic acid,2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-; 2-[(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)methoxy]acetic acid; Acetic acid, ((2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy)-Smiles
C1=NC2=C(N1COCC(=O)O)N=C(NC2=O)NDescription
It is a putative neurotoxin and the main metabolite of Acyclovir that has been used in the treatment and prophylaxis of infections with herpes simplex virus and varicella-zoster virus.References
Hellden, A., et al. “High Serum Concentrations of the Acyclovir Main Metabolite 9-Carboxymethoxymethylguanine in Renal Failure Patients with Acyclovir-Related Neuropsychiatric Side Effects: An Observational Study.†Nephrology Dialysis Transplantation, vol. 18, no. 6, June 2003, pp. 1135–41, https://doi.org/10.1093/ndt/gfg119. Darville, J. M., et al. “Development, Evaluation and Application of an Isocratic High-Performance Liquid Chromatography (HPLC) Assay for the Simultaneous Determination ofRequest a Quote
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