80685-22-9: Acyclovir Impurity 6

Acyclovir Impurity 6 (CAS No: 80685-22-9) or 9-Carboxymethoxymethylguanine is a putative neurotoxin and the main metabolite of Acyclovir that has been used in the treatment and prophylaxis of infections with herpes simplex virus and varicella-zoster virus.

Additional information

Catalogue No.

VE007787

CAS No.

80685-22-9

Molecular Formula

C8H9N5O4

Molecular Weight

239.19 g/mol

IUPAC Name

9-Carboxymethoxymethylguanine ; 2-((2-amino-6-oxo-1, 6-dihydro-9H-purin-9-yl)methoxy)acetic acid

References

Hellden, A., et al. “High Serum Concentrations of the Acyclovir Main Metabolite 9-Carboxymethoxymethylguanine in Renal Failure Patients with Acyclovir-Related Neuropsychiatric Side Effects: An Observational Study.” Nephrology Dialysis Transplantation, vol. 18, no. 6, June 2003, pp. 1135–41, https://doi.org/10.1093/ndt/gfg119. Darville, J. M., et al. “Development, Evaluation and Application of an Isocratic High-Performance Liquid Chromatography (HPLC) Assay for the Simultaneous Determination of

Status

In-stock