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102728-64-3Acyclovir EP Impurity A
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| Catalogue No.: | VL13001 |
|---|---|
| CAS No.: | 102728-64-3 |
| Mol. Formula: | C10H13N5O4 |
| Mol. Weight: | 267.24 g/mol |
Additional information on CAS 102728-64-3
Parent drug
Acyclovir / ValciclovirIUPAC Name
2-[(2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]ethyl acetatePharmacopoeial Synonyms
Acyclovir Related Compound A; Valciclovir EP Impurity IOther Synonyms
O-Acetyl Acyclovir; 9-(2-Acetoxyethoxymethyl)guanine; 6H-Purin-6-one, 9-[[2-(acetyloxy)ethoxy]methyl]-2-amino-1,9-dihydro-; 2-[(2-amino-6-oxo-3H-purin-9-yl)methoxy]ethyl acetate; 9-(2-acetoxyethoxy)methylguanine; 2-((2-Amino-6-oxo-1H-purin-9(6H)-yl)methoxy)ethylacetateSmiles
CC(OCCOCN1C=NC2=C1N=C(N)NC2=O)=OInChI
InChI=1S/C10H13N5O4/c1-6(16)19-3-2-18-5-15-4-12-7-8(15)13-10(11)14-9(7)17/h4H,2-3,5H2,1H3,(H3,11,13,14,17)Description
Acyclovir EP Impurity A, also known as Acyclovir Related Compound A; Valciclovir EP Impurity I, in various pharmacopoeias, is a highly characterized standard. It meets strict regulatory requirements set by USP, EMA, JP, and BP, making it a crucial component in Abbreviated New Drug Applications (ANDA), New Drug Applications (NDA), and the commercial production of Acyclovir/ Valciclovir.
References
Huidobro, A. L., et al. “LC Methods for Acyclovir and Related Impurities Determination.†Journal of Pharmaceutical and Biomedical Analysis, vol. 37, no. 4, Apr. 2005, pp. 687–94, https://doi.org/10.1016/j.jpba.2004.11.039. Ilager, Davalasab, et al. “Synthesis of Ca-Doped ZnO Nanoparticles and Its Application as Highly Efficient Electrochemical Sensor for the Determination of Anti-Viral Drug, Acyclovir.†Journal of Molecular Liquids, vol. 322, Jan. 2021, p. 114552, https://dRequest a Quote
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