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Documentation
Includes: HPLC, MASS/LC-MS, 1H NMR, FT-IR, Potency, Structure Elucidation Report (SER), and additional analytical data depending on the product.
91702-61-3Acyclovir EP Impurity C
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| Catalogue No.: | VL13002 |
|---|---|
| CAS No.: | 91702-61-3 |
| Mol. Formula: | C8H11N5O3 |
| Mol. Weight: | 225.2 g/mol |
Additional information on CAS 91702-61-3
Parent drug
AcyclovirIUPAC Name
2-Amino-7-[(2-hydroxyethoxy) methyl]-1, 7-dihydro-6H-purin-6-one; N7-[(2- Hydroxyethoxy)methyl)guaninePharmacopoeial Synonyms
Aciclovir N7-IsomerOther Synonyms
N7-((2-Hydroxyethoxy)methyl)guanine; 2-Amino-7-((2-hydroxyethoxy)methyl)-1H-purin-6(7H)-one; 6H-Purin-6-one, 2-amino-1,7-dihydro-7-[(2-hydroxyethoxy)methyl]-; 2-amino-7-(2-hydroxyethoxymethyl)-1H-purin-6-one; 2-amino-7-[(2-hydroxyethoxy)methyl]-6,7-dihydro-1H-purin-6-one; 7-(2-Hydroxyethoxymethyl)guanineSmiles
C1=NC2=C(N1COCCO)C(=O)NC(=N2)NInChI
InChI=1S/C8H11N5O3/c9-8-11-6-5(7(15)12-8)13(3-10-6)4-16-2-1-14/h3,14H,1-2,4H2,(H3,9,11,12,15)Description
Acyclovir EP Impurity C also referred to in pharmacopoeias as Aciclovir N7-Isomer, is a meticulously characterized reference standard. It adheres to stringent regulatory guidelines, including those established by USP, EMA, JP, and BP. This product plays a vital role in Abbreviated New Drug Applications (ANDA), New Drug Applications (NDA), and the commercial manufacturing of Acyclovir. Furthermore, it is accompanied by a comprehensive Structure Elucidation Report (SER), ensuring its accuracy and reliability across various analytical applications. Acyclovir EP Impurity C (CAS No: 91702-61-3) or 7-Acyclovir Impurity / Acyclovir N7-Isomer is an impurity observed while synthesis of acyclovir that is broadly used as an antiviral agent whose high concentration in the human body produces nausea and diarrhea.
References
Huidobro, A. L., et al. “LC Methods for Acyclovir and Related Impurities Determination.†Journal of Pharmaceutical and Biomedical Analysis, vol. 37, no. 4, Apr. 2005, pp. 687–94, https://doi.org/10.1016/j.jpba.2004.11.039. Ilager, Davalasab, et al. “Synthesis of Ca-Doped ZnO Nanoparticles and Its Application as Highly Efficient Electrochemical Sensor for the Determination of Anti-Viral Drug, Acyclovir.†Journal of Molecular Liquids, vol. 322, Jan. 2021, p. 114552, https://dRequest a Quote
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