Amiodarone EP Impurity B
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Documentation

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Includes: HPLC, MASS/LC-MS, 1H NMR, FT-IR, Potency, Structure Elucidation Report (SER), and additional analytical data depending on the product.

96027-74-6Amiodarone EP Impurity B

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Catalogue No.:VL1390002
CAS No.:96027-74-6
Mol. Formula:C23H26ClI2NO3
Mol. Weight:653.72 g/mol

Additional information on CAS 96027-74-6

Parent drug

Amiodarone

IUPAC Name

(2-Butylbenzofuran-3-yl)[4-[2-(ethylamino)ethoxy]-3, 5-diiodophenyl]methanone hydrochloride

Synonyms

Amiodarone related Compound B/ N-Desethyl Amiodarone Hydrochloride

Description

Amiodarone EP Impurity B (CAS No: 96027-74-6) or Amiodarone related Compound B/ N-Desethyl Amiodarone Hydrochloride is an impurity produced during the synthesis of Amiodarone that is an influential antiarrhythmic agent applied to treat ventricular arrhythmias and atrial fibrillation.

References

Karmarkar, S., et al. “Quality by Design (QbD) Based Development and Validation of an HPLC Method for Amiodarone Hydrochloride and Its Impurities in the Drug Substance.” Journal of Pharmaceutical and Biomedical Analysis, vol. 100, Nov. 2014, pp. 167–74, https://doi.org/10.1016/j.jpba.2014.07.002.

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