117796-52-8: Desloratadine N-Acetyl Impurity

117796-52-8: Desloratadine N-Acetyl Impurity

Desloratadine N-Acetyl Impurity (CAS No.: 117796-52-8) or 1-Acetyl-4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidine is a derivative of Desloratadine and is a neutral compound in this mobile phase. Desloratadine is a nonsedating antihistamine and is evaluated for the treatment of symptoms seen with seasonal allergic rhinitis (SAR), perennial allergic rhinitis (PAR), and chronic idiopathic urticaria (CIU) in patients aged above 12 years.

Additional information on CAS 117796-52-8

Catalogue No.

VL41004
CAS No.

117796-52-8
Molecular Formula

C21H21ClN2O
Molecular Weight

352.13
Parent drug

Desloratadine
IUPAC Name

1-[4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinyl]-ethanone
Synonyms

Loratadine N-Acetyl Impurity; 1-[4-(8-Chloro-5, 6-dihydro-11H-benzo[5, 6]cyclohepta[1, 2-b]pyridin-11-ylidene)-1-piperidinyl]-ethanone; 1-Acetyl-4-(8-chloro-5, 6-dihydro-11H-benzo[5, 6]cyclohepta[1, 2-b]pyridin-11-ylidene)-piperidine;
References

Zheng, Jinjian, and Abu M. Rustum. “Rapid Separation of Desloratadine and Related Compounds in Solid Pharmaceutical Formulation Using Gradient Ion-Pair Chromatography.” Journal of Pharmaceutical and Biomedical Analysis, vol. 51, no. 1, Jan. 2010, pp. 146–52, https://doi.org/10.1016/j.jpba.2009.08.024.? Limon, Lynn, and Denise R. Kockler. “Desloratadine: A Nonsedating Antihistamine.” Annals of Pharmacotherapy, vol. 37, no. 2, Feb. 2003, pp. 237–46, https://doi.org/10.1177/106002800303700216.?
Status

In-stock

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117796-52-8: Desloratadine N-Acetyl Impurity

117796-52-8: Desloratadine N-Acetyl Impurity
Catalogue No.

VL41004
CAS No.

117796-52-8
Molecular Formula

C21H21ClN2O
Molecular Weight

352.13
Parent drug

Desloratadine
IUPAC Name

1-[4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinyl]-ethanone
Synonyms

Loratadine N-Acetyl Impurity; 1-[4-(8-Chloro-5, 6-dihydro-11H-benzo[5, 6]cyclohepta[1, 2-b]pyridin-11-ylidene)-1-piperidinyl]-ethanone; 1-Acetyl-4-(8-chloro-5, 6-dihydro-11H-benzo[5, 6]cyclohepta[1, 2-b]pyridin-11-ylidene)-piperidine;
References

Zheng, Jinjian, and Abu M. Rustum. “Rapid Separation of Desloratadine and Related Compounds in Solid Pharmaceutical Formulation Using Gradient Ion-Pair Chromatography.” Journal of Pharmaceutical and Biomedical Analysis, vol. 51, no. 1, Jan. 2010, pp. 146–52, https://doi.org/10.1016/j.jpba.2009.08.024.? Limon, Lynn, and Denise R. Kockler. “Desloratadine: A Nonsedating Antihistamine.” Annals of Pharmacotherapy, vol. 37, no. 2, Feb. 2003, pp. 237–46, https://doi.org/10.1177/106002800303700216.?
Status

In-stock
ListName

Desloratadine N-Acetyl Impurity
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