1193725-73-3: Desloratadine N-Hydroxypiperidine
Desloratadine N-Hydroxypiperidine (CAS No.: 1193725-73-3) or N-Hydroxy Derivative of Desloratadine is an N-hydroxy derivative of Desloratadine which is a nonsedating selective H1-antihistamine and is proven to be efficacious and rapidly and safely reduced the symptoms during the treatment of perennial allergic rhinitis.
Additional information on CAS 1193725-73-3
VL41003
1193725-73-3
C₁₉H₁₉ClN₂O
326.82
Desloratadine
4-(8-chloro-5, 6-dihydro-11H-benzo[5, 6]cyclohepta[1, 2-b]pyridin-11-ylidene)piperidin-1-ol
N-Hydroxy Derivative of Desloratidine; 8-Chloro-6, 11-dihydro-11-(1-hydroxy-4-piperidinylidene)-5H-benzo[5, 6]cyclohepta[1, 2-b]pyridine;
“Biotransformation and Bioactivation Reactions of Alicyclic Amines in Drug Molecules.” Drug Metabolism Reviews, 2014, http://www.tandfonline.com/doi/abs/10.3109/03602532.2014.924962.?Simons, F. Estelle. R., et al. “Efficacy and Safety of Desloratadine in the Treatment of Perennial Allergic Rhinitis.” Journal of Allergy and Clinical Immunology, vol. 111, no. 3, Mar. 2003, pp. 617–22, https://doi.org/10.1067/mai.2003.168.?
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