2036-77-3: Dexamethasone EP Impurity J

Dexamethasone EP Impurity J (CAS No.: 2036-77-3) or 16a-Methyl-11-oxo Prednisolone is a metabolite of Dexamethasone which is a drug of choice for the treatment (particularly in preventing deafness)of infants and children with bacterial meningitis i.e inflammation of the protective membranes covering the brain and spinal cord.

Additional information

Catalogue No.

VE006073

CAS No.

2036-77-3

Molecular Formula

C22H28O5

Molecular Weight

372.45 g/mol

IUPAC Name

17, 21-Dihydroxy-16α-methylpregna-1, 4-diene-3, 11, 20-trione

Synonyms

16α-Methyl-11-oxo Prednisolone

References

Xu, Qun. “Incorporating Solid-Phase Extraction into Compendial Procedures for the Determination of Dexamethasone and Impurities in Low-Dose Drug Products.” Journal of Pharmaceutical and Biomedical Analysis, vol. 175, Oct. 2019, p. 112773, https://doi.org/10.1016/j.jpba.2019.07.021.?Lebel, Marc H., et al. “Dexamethasone Therapy for Bacterial Meningitis.” New England Journal of Medicine, vol. 319, no. 15, Oct. 1988, pp. 964–71, https://doi.org/10.1056/nejm198810133191502.?

Status

In-stock