Diltiazem EP Impurity D (Free Base)
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Documentation

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Includes: HPLC, MASS/LC-MS, 1H NMR, FT-IR, Potency, Structure Elucidation Report (SER), and additional analytical data depending on the product.

86408-45-9Diltiazem EP Impurity D (Free Base)

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Catalogue No.:VE0023237
CAS No.:86408-45-9
Mol. Formula:C21H24N2O4S
Mol. Weight:400.49 g/mol

Additional information on CAS 86408-45-9

Parent drug

Diltiazem

IUPAC Name

(2S, 3S)-2-(4-methoxyphenyl)-5-[2-(methylamino)ethyl]-4-oxo-2, 3, 4, 5-tetrahydro- 1, 5-benzothiazepin-3-yl Acetate

Pharmacopoeial Synonyms

Diltiazem Related Compound D

Other Synonyms

N-Desmethyl Diltiazem ;N-Monodemethyldiltiazem

Smiles

CC(O[C@]1([H])[C@@](C2=CC=C(OC)C=C2)([H])SC3=CC=CC=C3N(CCNC)C1=O)=O

InChI

InChI=1S/C21H24N2O4S/c1-14(24)27-19-20(15-8-10-16(26-3)11-9-15)28-18-7-5-4-6-17(18)23(21(19)25)13-12-22-2/h4-11, 19-20, 22H, 12-13H2, 1-3H3/t19-, 20+/m1/s1

Description

Diltiazem EP Impurity D (Free Base) also known as Diltiazem Related Compound D | in various pharmacopoeias | is a highly characterized standard. It meets strict regulatory requirements set by USP | EMA | JP | and BP | making it a crucial component in Abbreviated New Drug Applications (ANDA) | New Drug Applications (NDA) | and the commercial production of Diltiazem. To ensure precision and reliability in analytical applications | this impurity standard is supplied with a detailed Structure Elucidation Report (SER) | offering valuable insights for method development and quality control.

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