1160293-27-5: Dimethyl 2-(4-(methoxycarbonyl)-2-nitrophenyl)malonate

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Dimethyl 2-(4-(methoxycarbonyl)-2-nitrophenyl)malonate (CAS No. 1160293-27-5) is an impurity present in Nintedanib, nintedanib is a triple angiokinase inhibitor, which binds to the ATP-binding pocket of these receptors and inhibits their activity, Nintedanib also inhibits kinase signaling pathways in various cells within tumor tissues, which is used in the treatment of pulmonary fibrosis, systemic sclerosis-associated interstitial lung disease, and non-small cell lung cancer.

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Additional information on CAS 1160293-27-5

Catalogue No. VE009176
CAS No. 1160293-27-5
Molecular Formula C13H13NO8
Molecular Weight 311.24 g/mol
Parent drug Nintedanib
IUPAC Name dimethyl 2-(4-(methoxycarbonyl)-2-nitrophenyl)malonate
Synonyms N/A
References Rivera-Ortega, P., Hayton, C., Blaikley, J., Leonard, C., & Chaudhuri, N. (2018). Nintedanib in the management of idiopathic pulmonary fibrosis: clinical trial evidence and real-world experience. Therapeutic Advances in Respiratory Disease, 12, 175346661880061. https://doi.org/10.1177/1753466618800618
Status In-stock

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1160293-27-5: Dimethyl 2-(4-(methoxycarbonyl)-2-nitrophenyl)malonate

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