1160293-27-5: Dimethyl 2-(4-(methoxycarbonyl)-2-nitrophenyl)malonate

Dimethyl 2-(4-(methoxycarbonyl)-2-nitrophenyl)malonate (CAS No. 1160293-27-5) is an impurity present in Nintedanib, nintedanib is a triple angiokinase inhibitor, which binds to the ATP-binding pocket of these receptors and inhibits their activity, Nintedanib also inhibits kinase signaling pathways in various cells within tumor tissues, which is used in the treatment of pulmonary fibrosis, systemic sclerosis-associated interstitial lung disease, and non-small cell lung cancer.

Additional information on CAS 1160293-27-5

Catalogue No.

VE009176

CAS No.

1160293-27-5

Molecular Formula

C13H13NO8

Molecular Weight

311.24 g/mol

Parent drug

Nintedanib

IUPAC Name

dimethyl 2-(4-(methoxycarbonyl)-2-nitrophenyl)malonate

Synonyms

N/A

References

Rivera-Ortega, P., Hayton, C., Blaikley, J., Leonard, C., & Chaudhuri, N. (2018). Nintedanib in the management of idiopathic pulmonary fibrosis: clinical trial evidence and real-world experience. Therapeutic Advances in Respiratory Disease, 12, 175346661880061. https://doi.org/10.1177/1753466618800618

Status

In-stock