methyl (Z)-3-(((4-(2-(4-methylpiperazin-1-yl)-N-nitrosoacetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
methyl (Z)-3-(((4-(2-(4-methylpiperazin-1-yl)-N-nitrosoacetamido)phenyl)amino)(phenyl)methylene)-2-isoindoline-6-carboxylate or methyl (Z)-3-(((4-(2-(4-methylpiperazin-1-yl)-N-nitrosoacetamido)phenyl)amino)(phenyl)methylene)-2-isoindoline-6-carboxylate,is a triple angiokinase inhibitor , is a small molecule, competitive that used for the treatment of idiopathic pulmonary fibrosis,interstitial lung disease. it acts to inhibit platelet-derived growth factors and fibroblast growth factor receptors.
Additional information on methyl (Z)-3-(((4-(2-(4-methylpiperazin-1-yl)-N-nitrosoacetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
VE009404
N/A
C30H30N6O5
554.60 g/mol
Nintedanib
methyl (Z)-3-(((4-(2-(4-methylpiperazin-1-yl)-N-nitrosoacetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
N/A
Liu, Feng, et al. “Application of Nintedanib and Other Potential Anti-Fibrotic Agents in Fibrotic Diseases.” Clinical Science, vol. 133, no. 12, June 2019, pp. 1309–20, https://doi.org/10.1042/cs20190249.
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