1168152-07-5: (E)-Methyl 1-acetyl-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate

1168152-07-5: (E)-Methyl 1-acetyl-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate

(E)-Methyl 1-acetyl-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate (CAS No.1168152-07-5) is a triple angiokinase inhibitor, which binds to the ATP-binding pocket of these receptors and inhibits their activity, Nintedanib also inhibits kinase signaling pathways in various cells within tumor tissues, which is used in the treatment of pulmonary fibrosis, systemic sclerosis-associated interstitial lung disease, and non-small cell lung cancer.

Additional information on CAS 1168152-07-5

Catalogue No.

VE009172
CAS No.

1168152-07-5
Molecular Formula

C20H17NO5
Molecular Weight

351.35 g/mol
Parent drug

Nintedanib
IUPAC Name

(E)-Methyl 1-acetyl-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
Synonyms

N/A
References

Rivera-Ortega, P., Hayton, C., Blaikley, J., Leonard, C., & Chaudhuri, N. (2018). Nintedanib in the management of idiopathic pulmonary fibrosis: clinical trial evidence and real-world experience. Therapeutic Advances in Respiratory Disease, 12, 175346661880061. https://doi.org/10.1177/1753466618800618
Status

In-stock

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