1221-70-1: Doxylamine EP Impurity C
Doxylamine EP Impurity C or Doxylamine Succinate Impurity C (CAS No.1221-70-1) or N, N-dimethyl-2-[(RS)-1-phenyl(pyridine-2- yl)methoxy]ethanamine. Doxylamine is a H1 Antagonist. It is prescribed in a combination with pyridoxine for the treatment of nausea and vomitting.
Additional information on CAS 1221-70-1
VL38003
1221-70-1
C16H20N2O
256.34 g/mol
Doxylamine
N,N-dimethyl-2-[(1RS)-1-phenyl-1-(pyridin-2-yl)methoxy]ethanamine
Doxylamine Succinate Impurity C; Desmethyl Doxylamine; N, N-Dimethyl-2-(phenyl-2-pyridinylmethoxy)ethanamine
"Friedman, H., et al. “Clearance of the Antihistamine Doxylamine.” Clinical Pharmacokinetics, vol. 16, no. 5, May 1989, pp. 312–16, https://doi.org/10.2165/00003088-198916050-00003. ?Koren, Gideon, et al. “Effectiveness of Delayed-Release Doxylamine and Pyridoxine for Nausea and Vomiting of Pregnancy: A Randomized Placebo Controlled Trial.” American Journal of Obstetrics and Gynecology, vol. 203, no. 6, Dec. 2010, pp. 571.e1–7, https://doi.org/10.1016/j.ajog.2010.07.030.
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