1221-70-1: Doxylamine EP Impurity C

Status: In-stock

Doxylamine EP Impurity C or Doxylamine Succinate Impurity C (CAS No.1221-70-1) or N, N-dimethyl-2-[(RS)-1-phenyl(pyridine-2- yl)methoxy]ethanamine. Doxylamine is a H1 Antagonist. It is prescribed in a combination with pyridoxine for the treatment of nausea and vomitting.

Additional information on CAS 1221-70-1

Catalogue No. VL38003
CAS No. 1221-70-1
Molecular Formula C16H20N2O
Molecular Weight 256.34 g/mol
Parent drug Doxylamine
IUPAC Name N,N-dimethyl-2-[(1RS)-1-phenyl-1-(pyridin-2-yl)methoxy]ethanamine
Synonyms Doxylamine Succinate Impurity C; Desmethyl Doxylamine; N, N-Dimethyl-2-(phenyl-2-pyridinylmethoxy)ethanamine
References "Friedman, H., et al. “Clearance of the Antihistamine Doxylamine.” Clinical Pharmacokinetics, vol. 16, no. 5, May 1989, pp. 312–16, https://doi.org/10.2165/00003088-198916050-00003. ?Koren, Gideon, et al. “Effectiveness of Delayed-Release Doxylamine and Pyridoxine for Nausea and Vomiting of Pregnancy: A Randomized Placebo Controlled Trial.” American Journal of Obstetrics and Gynecology, vol. 203, no. 6, Dec. 2010, pp. 571.e1–7, https://doi.org/10.1016/j.ajog.2010.07.030.
Status In-stock

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1221-70-1: Doxylamine EP Impurity C

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