115623-21-7: Enalapril Diketopiperazine Acid

Enalapril Diketopiperazine Acid or (CAS No.115623-21-7) or (S)-2-((3S,8aS)-3-methyl-1,4-dioxohexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl)-4-phenylbutanoic acid. Enalapril is a prodrug that is hydrolyzed after absorption to form the active angiotensin-converting enzyme Enalaprilat. It is administered orally. It decreases blood pressure by lowering peripheral resistance without increasing heart rate. It is well tolerated and safe. It is well tolerated and safe.

Additional information

Catalogue No.

VL1360013

CAS No.

115623-21-7

Molecular Formula

C₁₈H₂₂N₂O₄

Molecular Weight

330.38

IUPAC Name

(S)-2-((3S, 8aS)-3-methyl-1, 4-dioxohexahydropyrrolo[1, 2-a]pyrazin-2(1H)-yl)-4-phenylbutanoic acid

References

"Davies, Richard O., et al. “Enalapril Worldwide Experience.” The American Journal of Medicine, vol. 77, no. 2, Aug. 1984, pp. 23–35, https://doi.org/10.1016/s0002-9343(84)80055-8. ?Todd, Peter A., and Karen L. Goa. “Enalapril.” Drugs, vol. 43, no. 3, Mar. 1992, pp. 346–81, https://doi.org/10.2165/00003495-199243030-00005. ?"

Status

In-stock