N-Nitroso Desmethyl Sumatriptan Impurity

Status: Under Development

It is an impurity present in Sumatriptan, Sumatriptan is a serotonin receptor agonist, sumatriptan constricts cranial blood vessels and prevents the release of vasoactive peptides, also is an agonist of 5-HT1B and 5-HT1D. which inhibits the release of pro-inflammatory neuropeptides. Sumatriptan decreases carotid arterial blood flow and increases blood flow velocity in the internal carotid artery and middle cerebral artery. which is used to treat migraine.

Additional information on N-Nitroso Desmethyl Sumatriptan Impurity

Catalogue No. VE0010179
Molecular Formula C13H18N4O3S
Molecular Weight 310.4 g/mol
Parent drug Sumatriptan
IUPAC Name N-methyl-1-(3-(2-(methyl(nitroso)amino)ethyl)-1H-indol-5-yl)methanesulfonamide
Synonyms N/A
References Derry, C. J., Derry, S., & Moore, R. A. (2012). Sumatriptan (oral route of administration) for acute migraine attacks in adults. Cochrane Database of Systematic Reviews, 2019(5). https://doi.org/10.1002/14651858.cd008615.pub2
Status Under Development

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