N-Nitroso Palbociclib

N-Nitroso Palbociclib is an impurity present in Palbociclib, Palbociclib highly selective cyclin-dependent kinase 4/6 inhibitor, Palbociclib in combination with endocrine therapy is a valuable emerging option for patients with HR+/HER2− advanced or metastatic breast cancer.

Additional information

Catalogue No.

VE009744

CAS No.

N/A

Molecular Formula

C24H28N8O3

Molecular Weight

476.53 g/mol

IUPAC Name

6-acetyl-8-cyclopentyl-5-methyl-2-((5-(4-nitrosopiperazin-1-yl)pyridin-2-yl)amino)pyrido[2, 3-d]pyrimidin-7(8H)-one

References

Serra, F., Lapidari, P., Quaquarini, E., Tagliaferri, B., Sottotetti, F., & Palumbo, R. (2019). Palbociclib in metastatic breast cancer: current evidence and real-life data. Drugs in Context, 8, 1–16. https://doi.org/10.7573/dic.212579

Status

In-stock