Naphazoline EP Impurity D
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Includes: HPLC, MASS/LC-MS, 1H NMR, FT-IR, Potency, Structure Elucidation Report (SER), and additional analytical data depending on the product.

22126-67-6Naphazoline EP Impurity D

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Catalogue No.:VL1510004
CAS No.:22126-67-6
Mol. Formula:C14H14N2
Mol. Weight:210.27

Additional information on CAS 22126-67-6

Parent drug

Naphazoline

IUPAC Name

2-(Naphthalen-2-ylmethyl)-4, 5-dihydro-1H-imidazole

Synonyms

N/A

Description

Naphazoline EP Impurity D (CAS No: 22126-67-6) is an impurity present in Naphazoline which is an alpha-adrenergic and sympathomimetic agent used in topical nasal or ophthalmic pharmaceutical formulations. It is a vasoconstrictor with a rapid and prolonged action in overcoming swelling and congestion when applied to mucous membranes.

References

“Development and Validation of a Capillary Electrophoretic Method for the Determination of Degradation Product in Naphazoline HCl Bulk Drug Substance.” Journal of Liquid Chromatography & Related Technologies, 2021, www.tandfonline.com/doi/abs/10.1080/10826079808003408.Wall, G. Michael. “Naphazoline Hydrochloride.” Analytical Profiles of Drug Substances and Excipients, 1992, pp. 307–44, https://doi.org/10.1016/s0099-5428(08)60396-2.

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