Nebivolol Impurity 2
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Documentation

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Includes: HPLC, MASS/LC-MS, 1H NMR, FT-IR, Potency, Structure Elucidation Report (SER), and additional analytical data depending on the product.

Nebivolol Impurity 2

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Catalogue No.:VL490014
CAS No.:N/A
Mol. Formula:C22H21F2NO4
Mol. Weight:401.41 g/mol

Additional information on Nebivolol Impurity 2

Parent drug

Nebivolol

IUPAC Name

2, 2′-azanediylbis(1-(6-fluorochroman-2-yl)ethan-1-one) hydrochloride

Synonyms

N/A

Description

Nebivolol Impurity 2 is an impurity present in the synthesis of Nebivolol which is a selective b1-adrenergic blocker that is an antihypertensive drug that improves endothelial function and decreases arterial stiffness which may contribute to a decrease in cardiovascular risk.

References

Chandrasekhar, S. “Enantioselective Total Synthesis of the Antihypertensive Agent (S, R, R, R)-Nebivolol.” Tetrahedron, vol. 56, no. 34, Aug. 2000, pp. 6339–44, https://doi.org/10.1016/s0040-4020(00)00572-x.?

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