Nebivolol Isomer at RRT 1.13 is an impurity present in the synthesis of Nebivolol which is a racemic mixture of equal amounts of d-nebivolol and l-nebivolol that is a cardioselective b1-adrenergic receptor antagonist, a third-generation beta-blockers used primarily in cardiovascular diseases.
References
Motaleb, M. A., et al. “Synthesis and Biological Evaluation of 125I-Nebivolol as a Potential Cardioselective Agent for Imaging v1-Adrenoceptors.†Journal of Radioanalytical and Nuclear Chemistry, vol. 289, no. 1, Apr. 2011, pp. 239–45, https://doi.org/10.1007/s10967-011-1069-z.?
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