Nebivolol SRRR Isomer is an impurity present in Nebivolol which is a v-blocker used for the treatment of hypertension. The unique pharmacologic properties of nebivolol include high specificity for the v-1 receptor and a nitric oxide-mediated vasodilatory effect.
References
Chandrasekhar, S. “Enantioselective Total Synthesis of the Antihypertensive Agent (S, R, R, R)-Nebivolol.†Tetrahedron, vol. 56, no. 34, Aug. 2000, pp. 6339–44, https://doi.org/10.1016/s0040-4020(00)00572-x.?Sule, Sachin S., and William Frishman. “Nebivolol.†Cardiology in Review, vol. 14, no. 5, Sept. 2006, pp. 259–64, https://doi.org/10.1097/01.crd.0000223651.03023.8e.?
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