894783-71-2: Nintedanib Carboxylic Acid
Nintedanib Carboxylic Acid (CAS No: 894783-71-2) is an impurity present in nintedanib which is a salt form of nintedanib ethane sulfonate that contains a carboxylic acid group linked to an indole ring is used for the treatment of several diseases, including IPF, hypertension, and ovarian cancer.
Additional information
VE006859
894783-71-2
C30H31N5O4
525.6
(3Z)-2, 3-Dihydro-3-[[[4-[methyl[(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-1H-Indole-6-carboxylic Acid
Jayagopal, Balaji, and Shivashankar Murugesh. “QbD-Mediated RP-UPLC Method Development Invoking an FMEA-Based Risk Assessment to Estimate Nintedanib Degradation Products and Their Pathways.” Arabian Journal of Chemistry, vol. 13, no. 9, Sept. 2020, pp. 7087–103, https://doi.org/10.1016/j.arabjc.2020.07.014.?
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