894783-71-2: Nintedanib Carboxylic Acid

Nintedanib Carboxylic Acid (CAS No: 894783-71-2) is an impurity present in nintedanib which is a salt form of nintedanib ethane sulfonate that contains a carboxylic acid group linked to an indole ring is used for the treatment of several diseases, including IPF, hypertension, and ovarian cancer.

Additional information

Catalogue No.

VE006859

CAS No.

894783-71-2

Molecular Formula

C30H31N5O4

Molecular Weight

525.6

IUPAC Name

(3Z)-2, 3-Dihydro-3-[[[4-[methyl[(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-1H-Indole-6-carboxylic Acid

References

Jayagopal, Balaji, and Shivashankar Murugesh. “QbD-Mediated RP-UPLC Method Development Invoking an FMEA-Based Risk Assessment to Estimate Nintedanib Degradation Products and Their Pathways.” Arabian Journal of Chemistry, vol. 13, no. 9, Sept. 2020, pp. 7087–103, https://doi.org/10.1016/j.arabjc.2020.07.014.?

Status

In-stock