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97963-62-7Pantoprazole EP Impurity C

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Catalogue No.:	VL125003
CAS No.:	97963-62-7
Mol. Formula:	C8H6F2N2OS
Mol. Weight:	216.21 g/mol

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Additional information on CAS 97963-62-7

Parent drug

Pantoprazole

IUPAC Name

5-(Difluoromethoxy)-1H-benzimidazole-2-thiol

Pharmacopeial Synonyms

Pantoprazole Related Compound C; Pantoprazole BP Impurity C

Synonyms

Pantoprazole Thiol Impurity; 5-(Difluoromethoxy)-2-mercapto-1H-benzimidazole

Smiles

SC1=NC2=CC(OC(F)F)=CC=C2N1

InChI

InChI=1S/C8H6F2N2OS/c9-7(10)13-4-1-2-5-6(3-4)12-8(14)11-5/h1-3,7H,(H2,11,12,14)

Shipping Condition

Ambient Temperature

Description

Pantoprazole EP Impurity C, also designated Pantoprazole BP Impurity C, Pantoprazole Related Compound C, or Pantoprazole Thiol Impurity, is the thiol precursor 5-(difluoromethoxy)-2-mercapto-1H-benzimidazole, CAS 97963-62-7. With formula C8H6F2N2OS and molecular weight 216.21 g/mol, it represents a key synthetic intermediate and process-related impurity associated with pantoprazole formation. Its presence typically reflects incomplete cyclization or residual precursor carryover rather than oxidative degradation. Owing to its polar benzimidazole-thiol functionality and potential low-level trace occurrence, characterization generally requires LC-MS/MS, HPLC with photodiode array detection, and, where needed, GC-MS after derivatization for definitive identity assignment.