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2115779-15-0Pantoprazole EP Impurity E
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| Catalogue No.: | VL125006 |
|---|---|
| CAS No.: | 2115779-15-0 |
| Mol. Formula: | C32H28F4N6O8S2 |
| Mol. Weight: | 764.72 g/mol |
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Additional information on CAS 2115779-15-0
Parent drug
PantoprazoleIUPAC Name
6,6′-bis (Difluoromethoxy)-2,2′-bis[[(3,4-dimethoxypyridin-2-yl)methyl]sulfinyl]-1H,1′H-5,5′-bibenzimidazolylSmiles
COC1=C(C(=NC=C1)CS(=O)C2=NC3=C(N2)C=C(C(=C3)OC(F)F)C4=CC5=C(C=C4OC(F)F)N=C(NInChI
InChI=1S/C32H28F4N6O8S2/c1-45-23-5-7-37-21(27(23)47-3)13-51(43)31-39-17-9-15(25(49-29(33)34)11-19(17)41-31)16-10-18-20(12-26(16)50-30(35)36)42-32(40-18)52(44)14-22-28(48-4)24(46-2)6-8-38-22/h5-12,29-30H,13-14H2,1-4H3,(H,39,41)(H,40,42)Pharmacopeial Synonyms
Pantoprazole Related Compound E; Pantoprazole BP Impurity ESynonyms
Pantoprazole Dimer; 5-(difluoromethoxy)-6-[6-(difluoromethoxy)-2-[(3,4-dimethoxypyridin-2-yl)methylsulfinyl]-3H-benzimidazol-5-yl]-2-[(3,4-dimethoxypyridin-2-yl)methylsulfinyl]-1H-benzimidazolePharmacopoeial Synonyms
Pantoprazole Related Compound E; Pantoprazole BP Impurity EOther Synonyms
Pantoprazole Dimer; 5-(difluoromethoxy)-6-[6-(difluoromethoxy)-2-[(3,4-dimethoxypyridin-2-yl)methylsulfinyl]-3H-benzimidazol-5-yl]-2-[(3,4-dimethoxypyridin-2-yl)methylsulfinyl]-1H-benzimidazoleDescription
Pantoprazole EP Impurity E, also designated Pantoprazole BP Impurity E, Pantoprazole Related Compound E, or Pantoprazole Dimer, is the dimeric bis-benzimidazole sulfide species associated with pantoprazole process chemistry and oxidative coupling of the benzimidazole sulfoxide framework. CAS 2115779-15-0 corresponds to C32H28F4N6O8S2, molecular weight 764.72 g/mol. Its structure contains two 3,4-dimethoxypyridylmethylsulfinyl substituents and two difluoromethoxy groups, making chromatographic resolution demanding. Quantification typically relies on reversed-phase LC-MS or LC-MS/MS, with UV detection alone often insufficient because of low-level occurrence and potential co-elution with related process impurities.Request a Quote
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