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265120-58-9Ropivacaine EP Impurity E

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Catalogue No.:	VE0018019
CAS No.:	265120-58-9
Mol. Formula:	C17H26N2O
Mol. Weight:	274.40 g/mol

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Additional information on CAS 265120-58-9

Parent drug

Ropivacaine

IUPAC Name

(−)-(S)-N-(2,6-Dimethylphenyl)-1(1-methylethyl)piperidine-2-carboxamide

Synonyms

Ropivacaine BP Impurity E; Ropivacaine N-Isopropyl Analog

Description

Ropivacaine EP Impurity E, also designated Ropivacaine BP Impurity E or Ropivacaine N-Isopropyl Analog, is the N-dealkylated tertiary amine analogue associated with ropivacaine-related synthetic impurity profiles. CAS 265120-58-9 corresponds to a neutral basic compound with molecular formula C17H26N2O and molecular weight 274.40 g/mol. Its occurrence is typically linked to incomplete alkylation control or amide-side-chain variant formation during manufacture. Because positional and structural isomers may coexist, confirmation generally requires LC-MS/MS with orthogonal HPLC-UV or GC-MS, and, where necessary, NMR characterization. It is evaluated within impurity specifications under pharmacopeial and ICH Q3A/Q3B frameworks.