Tofacitinib Nitroso Impurity 1

Tofacitinib Nitroso Impurity 1 Or 3-((3R,4R)-4-methyl-3-(methyl(7-nitroso-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidine-1-yl)-3-oxopropanenitrile,Tofacitinib Nitroso Impurity 1 is an impurity present in Tofacitinib. Tofacitinib is a small-molecule Janus-associated kinase inhibitor, which is used for the treatment of adult patients with moderate to severe rheumatoid arthritis, also it has had an inadequate response or intolerance to methotrexate therapy.

Additional information

Catalogue No.

VE009521

CAS No.

N/A

Molecular Formula

C16H19N7O2

Molecular Weight

341.4 g//mol

IUPAC Name

3-((3R, 4R)-4-methyl-3-(methyl(7-nitroso-7H-pyrrolo[2, 3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile

References

Cada, D. J., Demaris, K., Levien, T. L., & Baker, D. E. (2013). Tofacitinib. Hospital Pharmacy, 48(5), 413–424. https://doi.org/10.1310/hpj4805-413

Status

Under Development