Tofacitinib Nitroso Impurity 1
Tofacitinib Nitroso Impurity 1 Or 3-((3R,4R)-4-methyl-3-(methyl(7-nitroso-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidine-1-yl)-3-oxopropanenitrile,Tofacitinib Nitroso Impurity 1 is an impurity present in Tofacitinib. Tofacitinib is a small-molecule Janus-associated kinase inhibitor, which is used for the treatment of adult patients with moderate to severe rheumatoid arthritis, also it has had an inadequate response or intolerance to methotrexate therapy.
Additional information on Tofacitinib Nitroso Impurity 1
VE009521
N/A
C16H19N7O2
341.4 g//mol
Tofacitinib
3-((3R, 4R)-4-methyl-3-(methyl(7-nitroso-7H-pyrrolo[2, 3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile
N/A
Cada, D. J., Demaris, K., Levien, T. L., & Baker, D. E. (2013). Tofacitinib. Hospital Pharmacy, 48(5), 413–424. https://doi.org/10.1310/hpj4805-413
Under Development
