N-Nitroso Tofacitinib
It is an impurity present in Tofacitinib. Tofacitinib is a small-molecule Janus-associated kinase inhibitor, which is used for the treatment of adult patients with moderate to severe rheumatoid arthritis. Also it has had an inadequate response or intolerance to methotrexate therapy.
Additional information on N-Nitroso Tofacitinib
Catalogue No.
VE009521
CAS No.
N/A
Molecular Formula
C16H19N7O2
Molecular Weight
341.4 g//mol
Parent drug
Tofacitinib
IUPAC Name
3-((3R, 4R)-4-methyl-3-(methyl(7-nitroso-7H-pyrrolo[2, 3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile
Synonyms
Tofacitinib Nitroso Impurity 1
References
Cada, D. J., Demaris, K., Levien, T. L., & Baker, D. E. (2013). Tofacitinib. Hospital Pharmacy, 48(5), 413–424. https://doi.org/10.1310/hpj4805-413
Status
Under Development
