Chemically known as 2,2-Dipropylpentanenitrile. It is an impurity of Valproic acid that is a class I Histone deacetylases inhibitor. It produces differentiation of carcinoma cells transformed into hematopoietic progenitor cells and leukemic blasts in patients with acute leukemia.
References
Alsarra, Ibrahim A., et al. “Valproic Acid and Sodium Valproate: Comprehensive Profile.” Profiles of Drug Substances, Excipients and Related Methodology, 2005, pp. 209–40, https://doi.org/10.1016/s0099-5428(05)32008-9. Zgouras, Dimitrios, et al. “Modulation of Angiogenesis-Related Protein Synthesis by Valproic Acid.” Biochemical and Biophysical Research Communications, vol. 316, no. 3, Apr. 2004, pp. 693–97, https://doi.org/10.1016/j.bbrc.2004.02.105.
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