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内容: HPLC、MASS/LC-MS、1H NMR、FT-IR、含量、構造解析レポート（SER）、および製品に応じた追加分析データ。
73590-06-4Amoxicillin EP Impurity J
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| カタログ番号: | VL1970010 |
|---|---|
| CAS番号: | 73590-06-4 |
| 分子式: | C₃₂H₃₈N₆O₁₀S₂ |
| 分子量: | 730.81 g/mol |
に関する追加情報 CAS 73590-06-4
親薬物
AmoxicillinIUPAC名
(2R)-(2R)-2-(4-Hydroxyphenyl)glycyl-(2S)-2-[(2R,4S)-4-carboxy-5,5-dimethyl-2-thiazolidinyl]glycyl-N-[(2S,5R,6R)-2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-6-yl]-2-(4-hydroxyphenyl)glycinamide薬局方同義語
Amoxicillin Related Compound JOther Synonyms
Amoxicillin Dimer; Amoxicillin open ring dimerSmile
O=C(N)[C@H](C1=CC=C(O)C=C1)N(C(C([C@H]2SC(C)(C)[C@H](C(O)=O)N2)NC(C(C3=CC=C(O)C=C3)N)=O)=O)[C@H]4[C@@]5([H])SC(C)(C)[C@H](C(O)=O)N5C4=OInChI
InChI=1S/C32H38N6O10S2/c1-31(2)21(29(45)46)36-25(49-31)18(35-24(42)17(33)13-5-9-15(39)10-6-13)26(43)37(19(23(34)41)14-7-11-16(40)12-8-14)20-27(44)38-22(30(47)48)32(3,4)50-28(20)38/h5-12,17-22,25,28,36,39-40H,33H2,1-4H3,(H2,34,41)(H,35,42)(H,45,46)(H,47,48)/t17?,18?,19-,20+,21-,22-,25+,28+/m0/s1説明
Amoxicillin EP Impurity J known in pharmacopoeias Amoxicillin Related Compound J is a thoroughly characterized reference standard. It meets strict regulatory standards including those set by USP EMA JP and BP. This product is crucial for use in Abbreviated New Drug Applications (ANDA) New Drug Applications (NDA) and the commercial production of Amoxicillin. Additionally it comes with a detailed Structure Elucidation Report (SER) ensuring its precision and dependability for a variety of analytical uses. Amoxicillin EP Impurity J (CAS No: 73590-06-4) or Amoxicillin Dimer is an impurity of Amoxicillin that is an aminopenicillin having an antibacterial activity that is destroyed by gram-positive and gram-negative v-lactamases.
References
Valvo, L., et al. Development of a Simple Liquid Chromatographic Method with UV and Mass Spectrometric Detection for the Separation of Substances Related to Amoxicillin Sodium.â€Â Journal of Chromatography A, vol. 797, no. 1-2, Feb. 1998, pp. 311–16, https://doi.org/10.1016/s0021-9673(97)00952-7 Zhu, Yongxin, et al. Evaluation of Liquid Chromatography Methods for the Separation of Ampicillin and Its Related Substances.†Journal of Pharmaceutical and Biomedical Analysis, vol. 14, no. 5, Mar. 1996見積もり依頼
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