Eltrombopag Impurity 10은 Eltrombopag Amino Impurity로도 불리며, CAS 376592-93-7에 해당한다. 구조적으로는 3-(3-amino-2-hydroxyphenyl)benzoic acid로 정의되는 아닐린성 페놀 카복실산이며, 엘트롬보팍 골격과 연관된 화합물이다. 분자식은 C13H11NO3, 분자량은 229.24 g/mol이다. 이는 불완전한 아릴 커플링 또는 아미노화 단계에서 유래한 공정 관련 불순물, 또는 합성 중간체 잔류물로 해석될 수 있다. 방향족 아미노기와 페놀기는 크로마토그래피 분리를 복잡하게 하고 산화 경로를 촉진할 수 있다. 극미량 분석에는 일반적으로 LC-MS/MS, LC-HRMS, 필요 시 NMR 기반 구조 확인이 요구되며, UV 검출만으로는 충분하지 않다.
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![2'-methoxy-3'-nitro-[1,1'-biphenyl]-3-carboxylic acid](https://veeprho.com/wp-content/uploads/2026/04/2-methoxy-3-nitro-11-biphenyl-3-carboxylic-acid-376591-94-5-VE0024675-f8b9.png "2'-methoxy-3'-nitro-[1,1'-biphenyl]-3-carboxylic acid")
