Eltrombopag Impurity 10, también denominada Eltrombopag Amino Impurity, corresponde al CAS 376592-93-7 y se define estructuralmente como ácido 3-(3-amino-2-hidroxifenil)benzoico, un ácido carboxílico fenólico de tipo anilina relacionado con el esqueleto de eltrombopag. Con fórmula molecular C13H11NO3 y peso molecular de 229.24 g/mol, es compatible con un subproducto de proceso o un intermediario arrastrado por una arilación o aminación incompleta. Sus funciones amino y fenólica aromáticas pueden dificultar la separación cromatográfica y favorecer rutas oxidativas. La caracterización a nivel traza suele requerir LC-MS/MS, LC-HRMS y, cuando procede, confirmación estructural por RMN; la detección por UV por sí sola suele ser insuficiente.
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