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포함 사항: HPLC, MASS/LC-MS, 1H NMR, FT-IR, 함량, 구조 규명 보고서(SER), 그리고 제품에 따라 추가 분석 데이터가 제공됩니다.

68728-47-2Amoxicillin EP Impurity D (Sodium Salt)

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카탈로그 번호:	VL1970002
CAS 번호:	68728-47-2
분자식:	C16H20N3NaO6S
분자량:	405.4 g/mol

견적 요청

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모약물

Amoxicillin

IUPAC명

(4S)-2-[[[(2R)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino]carboxymethyl]-5, 5-dimethylthiazolidine-4-carboxylic Acid Sodium Salt

약전 동의어

Amoxicillin Related Compound D; Penicilloic Acids of Amoxicillin Sodium Salt

Other Synonyms

2-((2-Amino-2-(4-hydroxyphenyl)acetamido)(carboxy)methyl)-5,5-dimethylthiazolidine-4-carboxylicacid,sodiumsalt; Alpha-[[amino(4-hydroxyphenyl)acetyl]amino]-4-carboxy-5,5-dimethyl-2-thiazolidineacetic acid monosodium salt

SMILES

CC1(C(NC(S1)C(C(=O)O)NC(=O)C(C2=CC=C(C=C2)O)N)C(=O)[O-])C.[Na+]

InChI

InChI=1S/C16H21N3O6S.Na/c1-16(2)11(15(24)25)19-13(26-16)10(14(22)23)18-12(21)9(17)7-3-5-8(20)6-4-7;/h3-6,9-11,13,19-20H,17H2,1-2H3,(H,18,21)(H,22,23)(H,24,25);/q;+1/p-1

설명

Amoxicillin EP Impurity D also known as Amoxicillin Related Compound D; Penicilloic Acids of Amoxicillin Sodium Salt, in various pharmacopoeias, is a highly characterized standard. It meets strict regulatory requirements set by USP, EMA, JP, and BP, making it a crucial component in Abbreviated New Drug Applications (ANDA), New Drug Applications (NDA), and the commercial production of Amoxicillin.

References

Valvo, L., et al. Development of a Simple Liquid Chromatographic Method with UV and Mass Spectrometric Detection for the Separation of Substances Related to Amoxicillin Sodium.â€Â Journal of Chromatography A, vol. 797, no. 1-2, Feb. 1998, pp. 311â€“16, https://doi.org/10.1016/s0021-9673(97)00952-7 Zhu, Yongxin, et al. Evaluation of Liquid Chromatography Methods for the Separation of Ampicillin and Its Related Substances.â€ Journal of Pharmaceutical and Biomedical Analysis, vol. 14, no. 5, Mar. 1996