Azelaic Acid Inhouse Impurity D (CAS 1852-04-6) | também referida como undecanedioic acid | é uma impureza homóloga de cadeia C11 identificada no perfil de impurezas de azelaico. Quimicamente um diácido dicarboxílico linear | apresenta polaridade e solubilidade distintas que alteram o comportamento cromatográfico e o ponto de fusão do material final. Sua presença indica variação na matéria-prima ou reações secundárias durante oxidação e pode influenciar pureza | estabilidade e propriedades físico-químicas do lote. A detecção e quantificação são típicas por LC-MS | HPLC com detector apropriado ou GC-MS após derivatização. Estratégias de controlo incluem otimização de processo | purificação por cromatografia e critérios analíticos de especificação.
Referências
Breathnach, A.S. “Pharmacological Properties of Azelaic Acid.†Clinical Drug Investigation, vol. 10, no. Supplement 2, 1995, pp. 27–33, 10.2165/00044011-199500102-00005. Accessed 4 Feb. 2020.
Solicitar orçamento
"*" indica campos obrigatórios
Outros produtos relacionados às Azelaic Acid impurities
To provide the best experiences, we use technologies like cookies to store and/or access device information. Consenting to these technologies will allow us to process data such as browsing behavior or unique IDs on this site. Not consenting or withdrawing consent, may adversely affect certain features and functions.
Functional
Sempre ativo
The technical storage or access is strictly necessary for the legitimate purpose of enabling the use of a specific service explicitly requested by the subscriber or user, or for the sole purpose of carrying out the transmission of a communication over an electronic communications network.
Preferences
The technical storage or access is necessary for the legitimate purpose of storing preferences that are not requested by the subscriber or user.
Statistics
The technical storage or access that is used exclusively for statistical purposes.The technical storage or access that is used exclusively for anonymous statistical purposes. Without a subpoena, voluntary compliance on the part of your Internet Service Provider, or additional records from a third party, information stored or retrieved for this purpose alone cannot usually be used to identify you.
Marketing
The technical storage or access is required to create user profiles to send advertising, or to track the user on a website or across several websites for similar marketing purposes.
To provide the best experiences, we use technologies like cookies to store and/or access device information. Consenting to these technologies will allow us to process data such as browsing behavior or unique IDs on this site. Not consenting or withdrawing consent, may adversely affect certain features and functions.
Functional
Sempre ativo
The technical storage or access is strictly necessary for the legitimate purpose of enabling the use of a specific service explicitly requested by the subscriber or user, or for the sole purpose of carrying out the transmission of a communication over an electronic communications network.
Preferences
The technical storage or access is necessary for the legitimate purpose of storing preferences that are not requested by the subscriber or user.
Statistics
The technical storage or access that is used exclusively for statistical purposes.The technical storage or access that is used exclusively for anonymous statistical purposes. Without a subpoena, voluntary compliance on the part of your Internet Service Provider, or additional records from a third party, information stored or retrieved for this purpose alone cannot usually be used to identify you.
Marketing
The technical storage or access is required to create user profiles to send advertising, or to track the user on a website or across several websites for similar marketing purposes.
