Bisfenol A, CAS 80-05-7, é um composto aromático difenólico com fórmula C15H16O2 e massa molecular de 228.29 g/mol. Trata-se de um monómero industrial de grande volume utilizado na produção de policarbonatos e resinas epóxi, e a sua ocorrência como impureza está geralmente associada a material residual de síntese, libertação hidrolítica de matrizes poliméricas ou migração a partir de revestimentos internos e plásticos de consumo. A avaliação regulatória centra-se na atividade endócrina, toxicidade reprodutiva e persistência ambiental, e não na classificação como impureza genotóxica segundo ICH M7. A quantificação requer normalmente LC-MS/MS ou GC-MS, frequentemente com derivatização e diluição isotópica.
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