Salbutamol EP Impurity G (sal hidroclorídrico) | CAS 24085-08-3 | é uma impureza isolada na síntese e purificação do salbutamol | caracterizada por um núcleo fenólico com grupo benzil-terc-butilamino e função hidroximetilo. Identificada como Salbutamol BP Impurity G ou N-Benzyl Salbutamon | sua presença altera especificações de pureza e perfil cromatográfico do material ativo. Requer monitorização por métodos analíticos robustos como HPLC-UV | LC-MS e RMN para quantificação | identificação estrutural e avaliação de estabilidade. A compreensão de sua via de formação | níveis aceitáveis e estratégias de controle é essencial para conformidade com monografias e gestão de qualidade em processos farmacêuticos.
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