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15307-77-4Aceclofenac EP Impurity C

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Katalog-Nr.::	VL284006
CAS-Nr.::	15307-77-4
Summenformel::	C16H15Cl2NO2
Molare Masse::	324.2 g/mol

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Zusätzliche Informationen zu CAS 15307-77-4

Parent drug

Aceclofenac

IUPAC-Name

Ethyl [2-[(2, 6-dichlorophenyl)amino]phenyl]acetate

Pharmakopöe-Synonyme

Diclofenac Ethyl Ester

Other Synonyms

Aceclofenac Impurity C; Aceclofenac BP Impurity C; ethyl 2-[2-(2,6-dichloroanilino)phenyl]acetate; ethyl 2-(2-(2,6-dichlorophenylamino)phenyl)acetate; Benzeneacetic acid, 2-((2,6-dichlorophenyl)amino)-, ethyl ester;

Beschreibung

Aceclofenac EP Impurity C (CAS No: 15307-77-4) or Aceclofenac Impurity C / Diclofenac Ethyl Ester is formed during the production of Aceclofenac that is used In patients with osteoarthritis of the knee, basal and stimulated prostaglandin E2 production by blood mononuclear and polymorphonuclear cell inhibition.

References

Karbhari, PradnyaA, et al. “RP-LC Gradient Elution Method for Simultaneous Determination of Thiocolchicoside, Aceclofenac and Related Impurities in Tablet Formulation.” Journal of Pharmacy and Bioallied Sciences, vol. 6, no. 4, 2014, p. 246, https://doi.org/10.4103/0975-7406.142955. Brogden, Rex N., and Lynda R. Wiseman. “Aceclofenac.” Drugs, vol. 52, no. 1, July 1996, pp. 113–24, https://doi.org/10.2165/00003495-199652010-00008. ?