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127253-06-9Clarithromycin EP Impurity C

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Katalog-Nr.::	VL740001
CAS-Nr.::	127253-06-9
Summenformel::	C38H70N2O13
Molare Masse::	762.97 g/mol

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Zusätzliche Informationen zu CAS 127253-06-9

Parent drug

Clarithromycin

IUPAC-Name

6-O-Methylerythromycin A (E)-9-oxime

Pharmacopeial Synonyms

Clarithromycin 9-Oxime; Clarithromycin Impurity C

Other Synonyms

(3R,4S,5S,6R,7R,9R,11S,12R,13S,14R,E)-6-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-12,13-dihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-10-(hydroxyimino)-7-methoxy-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one

SMILES

O=C([C@H](C)[C@@H](O[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1)[C@H](C)[C@@H](O[C@H]2[C@H](O)[C@@H](N(C)C)C[C@@H](C)O2)[C@](C)(OC)C[C@H]/3C)O[C@H](CC)[C@@](C)(O)[C@H](O)[C@@H](C)C3=N\O

InChI

InChI=1S/C38H70N2O13/c1-15-26-38(10,45)31(42)21(4)28(39-46)19(2)17-37(9,48-14)33(53-35-29(41)25(40(11)12)16-20(3)49-35)22(5)30(23(6)34(44)51-26)52-27-18-36(8,47-13)32(43)24(7)50-27/h19-27,29-33,35,41-43,45-46H,15-18H2,1-14H3/b39-28+/t19-,20-,21+,22+,23-,24+,25+,26-,27+,29-,30+,31-,32+,33-,35+,36-,37-,38-/m1/s1

Beschreibung

Clarithromycin EP Impurity C (CAS No: 127253-06-9) or Clarithromycin 9-Oxime is an oxime derivative of Erythromycin. Erythromycin is a macrolide that functions by blocking the translocation reaction at the time of protein synthesis. Erythromycin, except under alkaline conditions, is inactive against Enterobacteriaceae and Pseudomonas aeruginosa.