Moxifloxacin EP Impurity C (HCl salt)
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1029364-75-7Moxifloxacin EP Impurity C (HCl salt)

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Katalog-Nr.::VL106003
CAS-Nr.::1029364-75-7
Summenformel::C22H27ClFN3O4
Molare Masse::451.92

Zusätzliche Informationen zu CAS 1029364-75-7

Parent drug

Moxifloxacin

IUPAC-Name

1-Cyclopropyl-8-ethoxy-6-fluoro-7-[(4aS,7aS)-octahydro-6H-pyrrolo [3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid HCl

Pharmakopöe-Synonyme

Moxifloxacin Related Compound C

Other Synonyms

8-Ethoxy Moxifloxacin (HCl Salt); Moxifloxacin HCl Ethyl Analog

SMILES

CCOC1=C2C(=CC(=C1N3C[C@@H]4CCCN[C@@H]4C3)F)C(=O)C(=CN2C5CC5)C(=O)O.Cl

InChI

InChI=1S/C22H26FN3O4.ClH/c1-2-30-21-18-14(20(27)15(22(28)29)10-26(18)13-5-6-13)8-16(23)19(21)25-9-12-4-3-7-24-17(12)11-25;/h8,10,12-13,17,24H,2-7,9,11H2,1H3,(H,28,29);1H/t12-,17+;/m0./s1

Beschreibung

Moxifloxacin EP Impurity C (HCl salt) (CAS No: 1029364-75-7) or Moxifloxacin Related Compound C is an impurity present in the synthesis of moxifloxacin which is a quinolone antimicrobial that has a potent activity that completely suppresses the Mycobacterium tuberculosis.

References

Al Omari, Mahmoud M. H., et al. “Moxifloxacin Hydrochloride.” Profiles of Drug Substances, Excipients and Related Methodology, 2014, pp. 299–431, https://doi.org/10.1016/b978-0-12-800173-8.00007-6. ?Gumbo, Tawanda, et al. “Selection of a Moxifloxacin Dose That Suppresses Drug Resistance InMycobacterium Tuberculosis, by Use of an in Vitro Pharmacodynamic Infection Model and Mathematical Modeling.” The Journal of Infectious Diseases, vol. 190, no. 9, Nov. 2004, pp. 1642–51, https://doi.org/10.1086

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