El dímero de cefalexina es una impureza de proceso formada por acoplamiento molecular de dos unidades de cefalexina durante síntesis o almacenamiento | que afecta la estabilidad y el perfil de impurezas del principio activo. Su identificación y cuantificación requieren técnicas analíticas como HPLC con detección UV | espectrometría de masas y NMR para confirmar masa y conectividad. La presencia del dímero puede indicar condiciones de reacción subóptimas | pH inadecuado o exposición a agentes oxidantes. El control se logra mediante optimización de parámetros de proceso | purificación cromatográfica y criterios de aceptación según directrices regulatorias. Monitoreo rutinario y estudios de degradación garantizan límites reproducibles y aceptables.
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