110671-78-8: 14- Hydroxy Clarithromycin

14 Hydroxy Clarithromycin (CAS No: 110671-78-8) is a metabolite of clarithromycin. Clarithromycin is an acid-stable and orally taken macrolide antimicrobial drug and is structurally similar to erythromycin. It has a broad spectrum of antimicrobial activity and blocks an array of Gram-positive and Gram-negative organisms especially atypical pathogens and some anaerobes.

Additional information on CAS 110671-78-8

Catalogue No.

VE008176

CAS No.

110671-78-8

Molecular Formula

C38H69NO14

Molecular Weight

763.96 g/mol

Parent drug

Clarithromycin

IUPAC Name

(3R, 4S, 5S, 6R, 7R, 9R, 11R, 12R, 13S, 14R)-6-(((2S, 3R, 4S, 6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-12, 13-dihydroxy-4-(((2R, 4R, 5S, 6S)-5-hydroxy-4-methoxy-4, 6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-14-(1-hydroxyethyl)-7-methoxy-3, 5, 7, 9, 11, 13-hexamethyloxacyclotetradecane-2, 10-dione

Synonyms

N/A

References

Baumann, Michaela, et al. “Aquatic Toxicity of the Macrolide Antibiotic Clarithromycin and Its Metabolites.” Chemosphere, vol. 120, Feb. 2015, pp. 192–98, https://doi.org/10.1016/j.chemosphere.2014.05.089. Peters, David H., and Stephen P. Clissold. “Clarithromycin.” Drugs, vol. 44, no. 1, July 1992, pp. 117–64, https://doi.org/10.2165/00003495-199244010-00009.

Status

In-stock