14- Hydroxy Clarithromycin
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Documentation

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Includes: HPLC, MASS/LC-MS, 1H NMR, FT-IR, Potency, Structure Elucidation Report (SER), and additional analytical data depending on the product.

110671-78-814- Hydroxy Clarithromycin

● Under development

Catalogue No.:VE008176
CAS No.:110671-78-8
Mol. Formula:C38H69NO14
Mol. Weight:763.96 g/mol

Additional information on CAS 110671-78-8

Parent drug

Clarithromycin

IUPAC Name

(3R, 4S, 5S, 6R, 7R, 9R, 11R, 12R, 13S, 14R)-6-(((2S, 3R, 4S, 6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-12, 13-dihydroxy-4-(((2R, 4R, 5S, 6S)-5-hydroxy-4-methoxy-4, 6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-14-(1-hydroxyethyl)-7-methoxy-3, 5, 7, 9, 11, 13-hexamethyloxacyclotetradecane-2, 10-dione

Synonyms

N/A

Description

14 Hydroxy Clarithromycin (CAS No: 110671-78-8) is a metabolite of clarithromycin. Clarithromycin is an acid-stable and orally taken macrolide antimicrobial drug and is structurally similar to erythromycin. It has a broad spectrum of antimicrobial activity and blocks an array of Gram-positive and Gram-negative organisms especially atypical pathogens and some anaerobes.

References

Baumann, Michaela, et al. “Aquatic Toxicity of the Macrolide Antibiotic Clarithromycin and Its Metabolites.” Chemosphere, vol. 120, Feb. 2015, pp. 192–98, https://doi.org/10.1016/j.chemosphere.2014.05.089. Peters, David H., and Stephen P. Clissold. “Clarithromycin.” Drugs, vol. 44, no. 1, July 1992, pp. 117–64, https://doi.org/10.2165/00003495-199244010-00009.

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