1315629-79-8: Atorvastatin-FX1 Impurity(Na Salt)

Also known as Atorvastatin Cyclo FP Impurity or 7-hydroxy analog is an impurity of atorvastatin. it is highly plasma protein bound (over 98%) and has a volume of distribution of about 380 liters and is metabolized by cytochrome P450 3A4 (CYP3A4) to active ortho- and para

Additional information on CAS 1315629-79-8

Catalogue No.

VL10021

CAS No.

1315629-79-8

Molecular Formula

C33H34FN2O7.Na

Molecular Weight

590.64g/mol (Acid); 612.22g/mol (Na Salt)

Parent drug

Atorvastatin

IUPAC Name

4-(1b-(4-fluorophenyl)-7-hydroxy-7-isopropyl-1a-phenyl-7a- (phenylcarbamoyl)hexahydro-1aH-oxireno[2’, 3’:3, 4]pyrrolo[2, 1- b][1, 3]oxazin-3-yl)-3-hydroxybutanoic acid Sodium salt

Synonyms

Atorvastatin Cyclo FP Impurity; 7-hydroxy analog

References

McIver, Lindsey A., and Momin S. Siddique. Atorvastatin.” Nih.gov, StatPearls Publishing, 5 Jan. 2019, http://www.ncbi.nlm.nih.gov/books/NBK430779/. Black, Donald M., et al. An Overview of the Clinical Safety Profile of Atorvastatin (Lipitor), a New HMG-CoA Reductase Inhibitor.” Archives of Internal Medicine, vol. 158, no. 6, Mar. 1998, p. 577, https://doi.org/10.1001/archinte.158.6.577.

Status

In-stock

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1315629-79-8: Atorvastatin-FX1 Impurity(Na Salt)

1315629-79-8: Atorvastatin-FX1 Impurity(Na Salt)
Catalogue No.

VL10021

CAS No.

1315629-79-8

Molecular Formula

C33H34FN2O7.Na

Molecular Weight

590.64g/mol (Acid); 612.22g/mol (Na Salt)

Parent drug

Atorvastatin

IUPAC Name

4-(1b-(4-fluorophenyl)-7-hydroxy-7-isopropyl-1a-phenyl-7a- (phenylcarbamoyl)hexahydro-1aH-oxireno[2’, 3’:3, 4]pyrrolo[2, 1- b][1, 3]oxazin-3-yl)-3-hydroxybutanoic acid Sodium salt

Synonyms

Atorvastatin Cyclo FP Impurity; 7-hydroxy analog

References

McIver, Lindsey A., and Momin S. Siddique. Atorvastatin.” Nih.gov, StatPearls Publishing, 5 Jan. 2019, http://www.ncbi.nlm.nih.gov/books/NBK430779/. Black, Donald M., et al. An Overview of the Clinical Safety Profile of Atorvastatin (Lipitor), a New HMG-CoA Reductase Inhibitor.” Archives of Internal Medicine, vol. 158, no. 6, Mar. 1998, p. 577, https://doi.org/10.1001/archinte.158.6.577.

Status

In-stock

ListName

Atorvastatin-FX1 Impurity(Na Salt)

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