345891-62-5: Atorvastatin EP Impurity K

Also known as Atorvastatin Methyl Ester or Diol methyl ester impurity, it is an impurity of Atorvastatin and is used to reduce reducing both cholesterols and reduce the raised lipid levels in patients with primary hyperlipidemia. It is used to prevent and treatment of cardiovascular disease at high risk and to treat abnormal lipid levels.

Additional information on CAS 345891-62-5

Catalogue No.

VL10009

CAS No.

345891-62-5

Molecular Formula

C₃₄H₃₇FN₂O₅

Molecular Weight

572.67

Parent drug

Atorvastatin

IUPAC Name

(3S, 5R)-7-[3-(Phenylcarbamoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl]-3, 5-dihydroxyheptanoic acid methyl ester

Synonyms

Atorvastatin Methyl Ester; Diol methyl ester impurity

References

Zarganes-Tzitzikas, Tryfon, et al. 'Atorvastatin (Lipitor) by MCR.' ACS Medicinal Chemistry Letters, vol. 10, no. 3, Feb. 2019, pp. 389–92, https://doi.org/10.1021/acsmedchemlett.8b00579. Woo, Jong Shin, et al. 'Comparison of the Efficacy and Safety of Atorvastatin 40 Mg/o-3 Fatty Acids 4 G Fixed-Dose Combination and Atorvastatin 40 Mg Monotherapy in Hypertriglyceridemic Patients Who Poorly Respond to Atorvastatin 40 Mg Monotherapy: An 8-Week, Multicenter, Randomized, Double-Blind Phase III Stud

Status

In-stock

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345891-62-5: Atorvastatin EP Impurity K

345891-62-5: Atorvastatin EP Impurity K
Catalogue No.

VL10009

CAS No.

345891-62-5

Molecular Formula

C₃₄H₃₇FN₂O₅

Molecular Weight

572.67

Parent drug

Atorvastatin

IUPAC Name

(3S, 5R)-7-[3-(Phenylcarbamoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl]-3, 5-dihydroxyheptanoic acid methyl ester

Synonyms

Atorvastatin Methyl Ester; Diol methyl ester impurity

References

Zarganes-Tzitzikas, Tryfon, et al. 'Atorvastatin (Lipitor) by MCR.' ACS Medicinal Chemistry Letters, vol. 10, no. 3, Feb. 2019, pp. 389–92, https://doi.org/10.1021/acsmedchemlett.8b00579. Woo, Jong Shin, et al. 'Comparison of the Efficacy and Safety of Atorvastatin 40 Mg/o-3 Fatty Acids 4 G Fixed-Dose Combination and Atorvastatin 40 Mg Monotherapy in Hypertriglyceridemic Patients Who Poorly Respond to Atorvastatin 40 Mg Monotherapy: An 8-Week, Multicenter, Randomized, Double-Blind Phase III Stud

Status

In-stock

ListName

Atorvastatin EP Impurity K

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