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22121-58-0Diclofenac EP Impurity B
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| Catalogue No.: | VL48010 |
|---|---|
| CAS No.: | 22121-58-0 |
| Mol. Formula: | C13H9Cl2NO |
| Mol. Weight: | 266.12 g/mol |
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Additional information on CAS 22121-58-0
Parent drug
DiclofenacIUPAC Name
2-[(2,6-Dichlorophenyl)amino]benzaldehydePharmacopeial Synonyms
Diclofenac Benzaldehyde Analog; Diclofenac Related Compound BSynonyms
o-(2,6-Dichloroanilino)benzaldehyde; Anthranilaldehyde, N-(2,6-dichlorophenyl)-Smiles
O=CC1=CC=CC=C1NC2=C(Cl)C=CC=C2ClInChI
InChI=1S/C13H9Cl2NO/c14-10-5-3-6-11(15)13(10)16-12-7-2-1-4-9(12)8-17/h1-8,16HShipping Condition
Ambient TemperatureDescription
Diclofenac EP Impurity B, also designated Diclofenac Related Compound B or Diclofenac Benzaldehyde Analog, is the aldehydic precursor o-(2,6-dichloroanilino)benzaldehyde, CAS 22121-58-0, with formula C13H9Cl2NO and molecular weight 266.12 g/mol. This aromatic amino benzaldehyde represents a synthetic intermediate and potential process-related impurity in diclofenac manufacture, arising from incomplete conversion or side-chain oxidation before formation of the phenylacetic acid motif. Its carbonyl function and dichloroanilino substituent make it chemically distinct from the active drug. Trace-level determination typically relies on LC-MS/MS, LC-UV with impurity-specific separation, and, where needed, GC-MS after derivatization.Request a Quote
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