122861-53-4: Doxycycline EP Impurity F
Also known as 2-Acetyl-2-Decarbamoyldoxycycline (CAS No. 122861-53-4). It is from the second-generation Tetracycline class of antibiotics. It is a synthetic derivative of oxytetracycline. Its absorption decreases with the antacids.
Additional information on CAS 122861-53-4
VL159002
122861-53-4
C23H25NO8
443.45
Doxycycline
4S, 4aR, 5S, 5aR, 6R, 12aS)-2-acetyl-4-(dimethylamino)-3, 5, 10, 12, 12a-pentahydroxy- 6-methyl-4a, 5a, 6, 12a-tetrahydrotetracene-1, 11(4H, 5H)-dione
2-Acetyl-2-Decarbamoyldoxycycline
'Smith, kelly, and James J. Leyden. “Safety of Doxycycline and Minocycline: A Systematic Review.” Clinical Therapeutics, vol. 27, no. 9, Sept. 2005, pp. 1329–42, https://doi.org/10.1016/j.clinthera.2005.09.005. ?Saivin, S., and G. Houin. “Clinical Pharmacokinetics of Doxycycline and Minocycline.” Clinical Pharmacokinetics, vol. 15, no. 6, Dec. 1988, pp. 355–66, https://doi.org/10.2165/00003088-198815060-00001 '
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