91-02-1: Doxylamine EP Impurity D
Doxylamine EP Impurity D or 2-Benzoylpyridine( CAS No. 91-02-1) or Phenyl(pyridin-2-yl)methanone (2-benzoylpyridine). Doxylamine is an H1 Antagonist. It is prescribed in a combination with pyridoxine for the treatment of nausea and vomiting.
Additional information on CAS 91-02-1
N, N-Dimethyl-2-[1-phenyl-1-(2-pyridinyl)ethoxy]ethanamine N-oxide
2-Benzoylpyridine; Doxylamine Ethylamine N-Oxide; Phenyl-2-pyridinyl-methanone; 2-Benzoylpyridine; 2-Pyridyl Phenyl Ketone; NSC 20887; Phenyl 2-pyridyl Ketone; Phenyl(2-pyridinyl)methanone
Friedman, H., et al. “Clearance of the Antihistamine Doxylamine.” Clinical Pharmacokinetics, vol. 16, no. 5, May 1989, pp. 312–16, https://doi.org/10.2165/00003088-198916050-00003. Koren, Gideon, et al. “Effectiveness of Delayed-Release Doxylamine and Pyridoxine for Nausea and Vomiting of Pregnancy: A Randomized Placebo Controlled Trial.” American Journal of Obstetrics and Gynecology, vol. 203, no. 6, Dec. 2010, pp. 571.e1–7, https://doi.org/10.1016/j.ajog.2010.07.030.
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